EmbryoGlue®

EmbryoGlue®

Implantation promoting medium for increased take-home baby rate.

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Optimised transfer

Embryo transfer is one of the most sensitive and critical procedures in IVF treatment. EmbryoGlue is a medium developed exclusively for embryo transfer and the only existing product with a proven implantation-enhancing effect1.

EmbryoGlue has the basic composition of a rich blastocyst culture medium and contains a high concentration of hyaluronan and recombinant human albumin. It is uniquely developed to mimic the conditions in the female uterus in order to help embryos implant after transfer.

Proven effect

When EmbryoGlue was used for embryo transfer the clinical pregnancy rate was significantly increased from 41% to 50% compared to when a conventional culture medium with low or no hyaluronan was used.

The meta-analysis of the 13 publications included in the Cochrane review article included more than 3200 patients. Importantly, the analysis did not show any increase in miscarriages or other adverse events. The conclusion by the Cochrane authors was that “a clear positive effect (of having high concentrations of hyaluronan in the transfer medium) was identified”. 

EmbryoGlue_clinical pregnancy rate

EmbryoGlue increases the chance of having a baby

See the movie when Laboratory Director Basak Balaban from American Hospital of Istanbul in Turkey explains how using EmbryoGlue for transfer can increase the chance to have a baby.  

How does is work?

EmbryoGlue contains all nutrients and energy sources needed for an optimal embryo development. It contains a high concentration of implantation promoting hyaluronan, which is the major glycosaminoglycan present in the follicular, oviductal and uterine fluids3, 4, 5. The physiological concentrations in these fluids provide high viscosity environments in the oviduct and uterus6.

The synthesis of hyaluronan increases dramatically on the day of implantation and decreases to near basal levels by the next day, indicating that it is important for implantation. 

Do you want to learn more? 

Download a white paper that further describes what makes EmbryoGlue a successful transfer medium.

Download white paper

Optimise all the way

Increase the chances of success at each stage of IVF. Ensure optimal conditions before, during and after culture by using the whole G-Series™. All G-Series media share the same basic composition to secure viability and implantation potential. Osmolality, pH and supporting compounds are all kept constant. This foundation prevents intracellular stresses as the embryos progress through the IVF process.

G-series_optimise all the way

G-Series - confidence at each step

Each product in the G-Series is developed to resemble conditions in the female reproductive tract and fulfil embryo requirements. 

 

REF: 1. Bontekoe et al. Adherence compounds in embryo transfer media for assisted reproductive technologies (Review). The Cochrane Collaboration 2014. Published by John Wiley & Sons, Ltd. 2. Bontekoe et al. Adherence compounds in embryo transfer media for assisted reproductive technologies (Review). The Cochrane Collaboration 2014. 3Lee and Ax. (1984). J Dairy Science 67. 4.Suchanek et al. (1994). Fert Steril 62. 5. Rodiguez-Martinez et al. (1998). In Gametes: Development and Function, Serono symposia. 6. Kano et al. (1998). Biol of Reprod 58.

Product description
Type Description
PurposeFor embryo transfer.
DescriptionBicarbonate buffered medium containing hyaluronan and recombinant human albumin.
ApplicationFor use after pre-equilibration at +37ºC and 6 % CO2.
StorageStore dark at +2 to +8ºC.