Clinical study with good results using STEEN Solution™ published in prestigious scientific journal

2011-06-09 - 11:30

In a landmark study recently published in the New England Journal of Medicine (, surgeons at Toronto General Hospital reported one-year outcomes of patients transplanted with initially rejected donor lungs after ex vivo lung perfusion using STEEN Solution™. The most recent hospital to use the method is Sahlgrenska University Hospital in Gothenburg, Sweden.

In the Toronto study, lungs initially deemed unusable, were perfused with STEEN Solution™ outside of the donor´s body and transplanted into 22 patients.  

The rate of primary organ dysfunction within 3 days after the transplant was only half in the STEEN Solution™ perfused group compared to the control group of 136 with conventionally treated lungs. Additionally, there were no severe adverse events that were directly attributable to the ex vivo procedure. The authors concluded that initially poor functioning donor lungs, when ex vivo perfused with STEEN Solution™, showed similar results one year after transplant to lungs obtained from standard, conventional donors.

Recently the Sahlgrenska University Hospital in Gothenburg, Sweden reported on their first four transplanted cases after use of STEEN Solution™ together with a new machine for normothermic lung perfusion.

Dr Göran Dellgren, chief of the heart and lung transplantation unit at Sahlgrenska University Hospital, is excited about the prospect that more organs now can be available for this life saving therapy.

The total number of lungs transplanted using STEEN Solution™ is to date more than 80. Magnus Nilsson CEO of XVIVO Perfusion AB is happy that the STEEN Solution™ is now in clinical use in the company's home town to the benefit for patients waiting for new lungs.

June 9, 2011


Magnus Nilsson


Queries should be addressed to:

Magnus Nilsson, CEO, phone +46 31 721 80 61

Anne-Lie Sveder, CFO, phone +46 31 721 80 13