When consumables and products used for ART are insufficiently quality controlled, they can contain components that are toxic to human reproductive cells such as gametes and embryos. This phenomenon can be referred to as reprotoxicity.
Dr. Martine Nijs has published a study on reprotoxicity testing of consumables and products in ART, which she was speaking about during Vitrolifes scientific symposium in conjunction to ESHRE 2011 in Stockholm.
Reprotoxicity can be described as the negative influence of components on the physiology and viability of human gametes and embryos. A delayed manifestation of reprotoxicity can result in reduced implantation rate and reduced on-going pregnancy rate and Dr. Nijs stressed the importance of testing of disposables used in the IVF-laboratory.
Reprotoxicity can be discovered through various tests, for example Mouse Embryo Assay and Human Sperm Survival Assay.