What is the EmbryoScope time-lapse system?
EmbryoScope is a certified tri-gas IVF incubator with a built-in camera developed to improve IVF treatments. The instrument is the result of more than 9 years of research and uses several proprietary technologies; it was approved for clinical use in the EU in June 2009 and was cleared by FDA (510k) in January 2011.
How does it work?
Hoffman modulation images of individual embryos are automatically recorded at preset time intervals. These images are compiled using specialised software to create a time-lapse sequence of embryodevelopment. Detailed information about timing of cell divisions, intervals between cell cycles and other important events including multinucleation, evenness of blastomeres and dynamic pronuclei patterns are annotated for analysis. This information is used by the embryologists to select the embryo that can be most likely to result in a pregnancy for transfer in an IVF treatment. Images are acquired without removing embryos from the incubator, and therefore manual handling of embryos outside the stable incubation conditions is minimised, leaving the embryos undisturbed at optimal growth conditions. Images and detailed information about incubation conditions are stored in patient data files for future reference.
How many clinics use the EmbryoScope time-lapse system?
The system has been widely adopted worldwide. More than 370 clinics are using this technology, many of which can be found on our “Find an EmbryoScope clinic” feature to locate an EmbryoScope clinic near you. Please note that not all EmbryoScope clinics are listed on the map.
Is the EmbryoScope time-lapse system approved (CE mark, FDA)?
All systems are manufactured in accordance with ISO13485 and have been CE-marked as a Class IIa Medical Device since 29 June 2009. FDA 510(k) clearance of the EmbryoScope time-lapse system was obtained in January 2011.
How many patients can be treated in the EmbryoScope time-lapse incubator?
The EmbryoScope incubator can hold six EmbryoSlide culture dishes with embryos from up to six different patients. Each EmbryoSlide culture dish can accommodate up to 12 embryos; consequently the EmbryoScope incubator can acquire time-lapse images of up to 72 embryos. The EmbryoScope time-lapse system has a capacity of 300 – 400 IVF treatment cycles per year per EmbryoScope instrument, depending on the duration of culture.
What are the experiences of using the EmbryoScope time-lapse system in a clinical setting?
Users at current fertility clinics find that the technology ultimately provides valuable flexibility in the daily routines of the clinic, because embryologists are free to carry out evaluations of embryo development at times that suit them and can easily consult other specialists or colleagues if necessary. Embryologists are able to use more time evaluating embryos, but less time with physical processes such as removing and replacing from the incubator and taking manual notes.