Meet the challenges in vitrification with RapidVit & RapidWarm Omni
Based on research and customer requirements, we have developed a solution that enables time-efficient, easy and successful vitrification for all cell stages.
The method, composition and design of RapidVit Omni™ and RapidWarm Omni™ build on many years of knowledge and experience in the field of cryopreservation. The products also fulfil the increasing demand from clinics for IVF solutions that are easy to use and save time.
RapidVit and RapidWarm Omni are used at physiological temperature
When using RapidVit and RapidWarm Omni, both vitrification and warming are performed at physiological temperature (37°C). This helps to maintain the spindle integrity and viability of oocytes and embryos.
Working at physiological temperatures shortens the vitrification time and minimises exposure of embryos to cryoprotectants and their potential toxic effects.
Optimal support for oocytes and embryos
RapidVit and RapidWarm Omni are designed using the G-Series™ cryo base medium. This is a MOPS buffered medium that contains Human Serum Albumin (HSA), amino acids, energy substrates and hyaluronan to fully support embryo metabolism and improve post-cryopreservation survival1.
The G-Series has been developed to resemble conditions in the female reproductive tract and fulfil embryo requirements, building on two decades of thorough research and clinical experience.
Easy to use – for all cell stages
RapidVit and RapidWarm Omni can be used for vitrification and warming of all cell stages, from the oocyte through to the blastocyst stage, and using the same media with cell-specific timings.
Working at room temperature (22–27°C) risks variation in the method that can be avoided by working at a set temperature of 37°C.
Protocols for RapidVit and RapidWarm Omni use large volumes of media. This improves success compared with methods using microdroplets by prolonging stable conditions, such as osmolality and temperature.
Simply move the embryos between wells in short, defined steps using ready-to-use media. This standardised approach with few handling steps reduces operator-related variation and decreases shear stress caused by manipulation.
Using RapidVit and RapidWarm Omni will save you time in every procedure. The graphs below compare the maximum times needed to vitrify using different brands.
Learn more about why 37⁰C is the optimal temperature for vitrification
We have summarised five studies that discuss the optimal temperature for vitrification. They all show that 37⁰C is the optimal temperature in order to not make damage to the spindle and to achieve good results. Click below to download the summary.
REF: 1. B. Balaban, B. Urman, B. Ata, A. Isiklar, M.G. Larman, R. Hamilton and D.K. Gardner, A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation, Hum Reprod. 2008 Sep;23(9):1976-82.