G-TL™

The first culture medium specifically designed for time-lapse.

Description Bicarbonate buffered medium containing hyaluronan and human serum albumin.

Purpose Medium for culture of embryos from fertilisation to the blastocyst stage.

Application For use after pre-equilibration at +37°C and 6 % CO2.

Storage Store dark at +2 to +8°C

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10145 G-TL™

For truly undisturbed time-lapse culture

Time-lapse culture removes time limits and stresses from embryos during assessment while adding power to classic morphology. G-TL is a medium in the G-Series™ designed to optimise the use of time-lapse technology, allowing truly undisturbed time-lapse culture.

Balancing stresses

G-TL provides uninterrupted culture conditions in an optimised culture environment to maximise embryo viability. The balanced mix of amino acids in G-TL is based on new knowledge about embryo metabolism and consumption of media constituents1. G-TL is designed to reduce ammonium load from breakdown products, while providing an optimised supply of amino acids for development. 

G-TL has been shown to give high results when compared to sequential culture systems as well as monophasic culture systems.

REF: 1. Wale and Gardner, Biology of Reproduction v2012;87(1):24, 1-8.


Why you should use specific
embryo culture media for
specific applications

Watch this movie where Dr. Silversand describes the development of G-TL as well as present clinical results from a multicentre prospective randomised trial.

Watch movie


Time-lapse technology triggers new requirements on embryo culture media

The introduction of time-lapse technology has reduced the need of handling the embryo outside the incubator. Time-lapse technology has given a unique possibility to balance metabolic stress against less handling stress during embryo culture. Learn more in this blog post.

Read blog post


Study confirms high
performance of G-TL

Watch Dr. Hardarson present results from an international, prospective, controlled and randomised multicentre study evaluating G-TL in a clinical environment using time-lapse technology. 
This lecture was a part of the Vitrolife Scientific Symposium at ESHRE 2014.

Optimise all the way with G-Series

Ensure optimal conditions before, during and after culture by using the whole G-Series. All G-Series media share the same basic composition to secure viability and implantation potential. Osmolality, pH and supporting compounds are all kept constant. This foundation prevents intracellular stresses as the embryos progress through the IVF process.

How to use this product

Package inserts
G-TL™

Package inserts

Package insert G-TL

Product manuals
G-TL™

Product manuals

Manual G-Series. International

Product manuals
G-TL™

Product manuals

Manual G-Series. For US

Additional documents

Short protocols
G-TL™

Short protocols

Short protocol - Embryo culture with G-TL and Primo Vision

This short protocol describes how to perform time-lapse culture using G-TL and PrimoVision

Short protocols
G-TL™

Short protocols

Short protocol - G-Series - Blastocyst trophectoderm biopsy

This short protocol describes how to perform blastocyst trophectoderm biopsy using G-2™ PLUS or G-TL™, OVOIL™ and G-MOPS™ PLUS

Scientific summaries
G-TL™

Scientific summaries

G-TL supports blastocyst development in large volume

In a study presented at the ACE meeting in the UK, Shaw and co-workers compared single step time-lapse medium (Vitrolife, G-TL) with sequential series media (Sage, Quinn’s advantage) in large volume culture as well as micro drop culture. They found significantly higher day 5 blastocyst development rate in the G-TL group in both large and small volume culture.

Safety data sheets (SDS)
G-TL™

Safety data sheets (SDS)

SDS G-TL

Safety data sheet for G-TL

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