From retrieval to transfer, you can help the egg and embryo develop by providing optimal culture conditions. After transfer, the embryo has to rely on mother’s receptivity and its own ability to implant. Using a hyaluronan-rich medium will promote a successful implantation. With EmbryoGlue, you can help Mother Nature and go the extra mile for your patients, helping them to bring a child home.
EmbryoGlue is the only existing product with a proven implantation-enhancing effect1. EmbryoGlue has the basic composition of a rich blastocyst culture medium and contains a high concentration of hyaluronan and recombinant human albumin. It can be used for transfer of all embryo developmental stages, including blastocysts after assisted hatching, biopsy and cryopreservation.
1. Bontekoe, S. et al.; The Cochrane database of systematic reviews 2014):2:CD007421
Since the introduction of EmbryoGlue in 2003, several studies have been published regarding its effect. The addition of a high concentration of hyaluronic acid (HA) in a transfer medium increases live births after IVF according to a meta-analysis1 from the independent research network Cochrane Collaboration.
When using EmbryoGlue for transfer, there was an overall absolute increase of 8% (19% relative increase) in the live birth rate, compared to a medium with low or no HA. The positive effect was seen regardless of embryo transfer day.
1. Bontekoe, S. et al.; The Cochrane database of systematic reviews 2014):2:CD007421
EmbryoGlue has been used for more than a million embryo transfers in clinics worldwide since 2003. EmbryoGlue is the most documented embryo transfer medium available on the market, with a proven track record of increased clinical outcomes.
3. Balaban, B. et al.; Hum. Reprod. (2011): 26(suppl 1): i24
4. Sun, HX et al.; J Reproduktionsmed Endokrinol (2010): 7(4): 303
Table showing numbers of studies included, pregnancy and implantation rate after EmbryoGlue compared to standard transfer medium for all cycles as well as cycles after cryopreservation or transfer of blastocyst stage.
4. Hashimoto S. et al. PP-009. ALPHA 2014. 10th Biannual conference, Antalya, Turkey
Read more about why hyaluronan is an invaluable molecule for embryo implantation in this blog post.
It makes perfect sense to use a medium that is specifically made for transfer.
Meet Stephen Harbottle, lead embryologist at Cambridge IVF and hear about how to increase the chance of a successful IVF treatment.
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