FreezeKit™ & ThawKit™ Cleave

The new generation of slow freezing – optimised composition, convenient protocol and high survival rate.

Description MOPS buffered media.

Application For use in sequence after equilibration at room temperature and ambient atmosphere.

Storage Store dark at +2 to +8°C.

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10166 FreezeKit™ Cleave
  • Purpose: For freezing of pronuclear oocytes and cleavage stage embryos. 
  • Disclaimer: This product is not cleared for sale in US.
10167 ThawKit™ Cleave
  • Purpose: For thawing of frozen pronuclear oocytes and cleavage stage embryos.
  • Disclaimer: This product is not cleared for sale in US.
10169 FreezeKit™ Cleave
  • Purpose: For freezing of pronuclear (2PN) and cleavage-stage embryos.
  • Disclaimer: Only for sale in the US.
10170 ThawKit™ Cleave
  • Purpose: For thawing of frozen pronuclear (2PN) and cleavage-stage embryos.
  • Disclaimer: Only for sale in the US.

New media composition

FreezeKit Cleave* and ThawKit Cleave* have been developed for freezing and thawing of pronuclear oocytes and cleavage stage embryos.

*US only: For freezing and thawing of pronuclear (2PN) and cleavage stage embryos.

Content in kit FreezeKit Cleave: 1x10 mL - Equilibration solution, 2x10 mL - Freezing solution. ThawKit Cleave: 1x10 mL - Thawing solution 1, 1x10 mL - Thawing solution 2, 1x10 mL - Equilibration solution

Time-saving and convenient

FreezeKit Cleave and ThawKit Cleave make the whole slow freezing procedure faster and more convenient. With fewer steps compared to the current protocol they save time, reduce operator variability and simplify the training process.

Most importantly, embryos are exposed to less stress with the fewer steps and shorter handling times.

Significantly higher blastocyst survival

Two clinics in Sweden made a pre-clinical, randomised comparison of FreezeKit Cleave and ThawKit Cleave with an existing commercial product for freezing of cleavage-stage embryos.

The primary endpoint was blastomere survival rate. A statistically significant difference in blastomere survival was seen between the two methods.

 

Does slowfreezing still have a role in cryopreservation in assisted reproduction?

Read guest blogger professor David Edgar's blog post about slow freezing and its role in cryopreservation.

Read blog post

How to use this product

Package inserts
FreezeKit™ & ThawKit™ Cleave

Package inserts

Package insert FreezeKit Cleave

Package inserts
FreezeKit™ & ThawKit™ Cleave

Package inserts

Package insert ThawKit Cleave

Product manuals
FreezeKit™ & ThawKit™ Cleave

Product manuals

Manual Cryopreservation

Additional documents

Short protocols
FreezeKit™ & ThawKit™ Cleave

Short protocols

Short protocols Slowfreezing - cleavage stage embryos

This short protocol describes how to perform slowfreezing on cleavage stage embryos using FreezeKit Cleave and ThawKit Cleave.

Scientific summaries
FreezeKit™ & ThawKit™ Cleave

Scientific summaries

New formulations of slowfreezing solutions for cleavage stage embryos result in outcomes similar to after vitrification.pdf

A study by Fang et al, found that FreezeKit Cleave and ThawKit Cleave significantly improved survival rates, clinical pregnancy rates and implantation rates. In fact, a survival rate of above 90% using the new formulations of solutions is very similar to that obtained after vitrification.

Safety data sheets (SDS)
FreezeKit™ & ThawKit™ Cleave

Safety data sheets (SDS)

SDS FreezeKit Cleave

Safety data sheet for FreezeKit Cleave

Safety data sheets (SDS)
FreezeKit™ & ThawKit™ Cleave

Safety data sheets (SDS)

SDS ThawKit Cleave

Safety data sheet for ThawKit Cleave

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