Rapid-i™ Vitrification System

For time-efficient, easy and successful vitrification.

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14406 Rapid-i™ Kit
  • Description: Vitrification device, transparent.
20-Pack
14419 Rapid-i™ Kit
  • Description: Vitrification device, red.
20-Pack
14420 Rapid-i™ Kit
  • Description: Vitrification device, green.
20-Pack
14421 Rapid-i™ Kit
  • Description: Vitrification device, blue.
20-Pack
14422 Rapid-i™ Kit
  • Description: Vitrification device, yellow.
20-Pack
14423 SmartBox 3™
  • Description: Box for liquid nitrogen, used with Rapid-i™ accessories.
  • Purpose: Hard shell box for working with Rapid-i™ outside LAF-hoods.
  • Application: For use with liquid nitrogen, Rapid-i Kit and Rapid-i accessories.
  • Disclaimer: Replaces SmartBox™ 14408 and SmartBox™ Mini 14418.
1-Pack
14414 Rapid-i™ Sealer
  • Description: Sealer PS-202, 120V
  • Purpose: Ultrasonic sealer for sealing Rapid-i Kits.
  • Application: For use with Rapid-i Kits after validation.
1-Pack
14415 Rapid-i™ Sealer
  • Description: Sealer PS-202, 230V
  • Purpose: Ultrasonic sealer for sealing Rapid-i Kits.
  • Application: For use with Rapid-i Kits after validation.
1-Pack
14417 Rapid-i™ CryoCane
  • Description: Metal cane for holding goblets used in cryopreservation
  • Purpose: For storage of Rapid-i™ Kit in cryotank, holds 1 goblet.
  • Application: For use with liquid nitrogen dewar and holder.
20-Pack
14416 Rapid-i™ Goblet
  • Description: Plastic goblet for holding straws used in cryopreservation.
  • Purpose: To hold Rapid-i™ Kit in cryopreservation storage.
  • Application: For use with liquid nitrogen dewar and holder.
20-Pack
14413 Rapid-i™ Cutter
  • Description: Cutter
  • Purpose: For opening of Rapid-i straw.
  • Application: For use with Rapid-i Kits in opening and retrieval.
1-Pack
14410 Rapid-i™ Forceps
  • Description: Forceps
  • Purpose: For retrieval of Rapid-i stick after opening.
  • Application: For use with Rapid-i Kits in opening and retrieval.
1-Pack
14408 SmartBox™
  • Description: Box for liquid nitrogen, used with Rapid-i™ accessories.
  • Purpose: Hard shell box for working with Rapid-i™ outside LAF-hoods.
  • Application: For use with liquid nitrogen, Rapid-i Kit and Rapid-i accessories.
  • Disclaimer: Is replaced by SmartBox 3™ REF 14423 Remaining stock will be available for sale until end of 2022 For more information, please contact customer support.
1-Pack
14418 SmartBox™ Mini
  • Description: Box for liquid nitrogen, used with Rapid-i™ accessories.
  • Purpose: Low-profile box adapted to working with Rapid-i™ LAF-hoods.
  • Application: For use with liquid nitrogen, Rapid-i Kit and Rapid-i accessories.
  • Disclaimer: Is replaced by SmartBox 3™ REF 14423 Remaining stock will be available for sale until end of 2022 For more information, please contact customer support.
1-Pack

Discover the Rapid-i™ Vitrification System – for safe, easy and successful vitrification

The Rapid-i Vitrification System has long been the natural choice for embryologists looking to optimise their vitrification workflow. The method, media, device, and accessories are all you need to simplify your workflow – from vitrification and storage to warming of oocytes and embryos.

Aseptic and closed system

Rapid-i Vitrification System is an aseptic and closed system removing the concerns regarding potential contamination from liquid nitrogen during transport and storage.

As the oocytes or embryos do not come in direct contact with liquid nitrogen, there is no need to sterilise liquid nitrogen. After vitrification, the RapidStraw is ultrasonically sealed providing safe storage.

Easy to use

The Rapid-i Kit is renowned for its simple handling. It supports a smooth workflow and eliminates risks of contamination during vitrification, storage and transport.

Oocytes or embryos are held by surface tension in a standardised volume. This simplifies loading and reduces variability between operators. It is easy to see when the right volume of medium has been applied.

Colour coded straws

To simplify identification and cryostorage management, the RapidStraws are available with five different colour codes; blue, green, red, yellow and transparent.

 

 

 

 

Media for every need

We provide media for vitrification and warming of all stages, from oocytes to blastocysts. Our vitrification media gives maximum support. It is based on the G-Series with amino acids and energy substrates that support embryo metabolism.

 

RapidVit™ & RapidWarm™ Blast

Media for vitrification and warming of blastocyst stage embryos.

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RapidVit™ & RapidWarm™ Oocyte

Media for vitrification and warming of oocytes.

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RapidVit™ & RapidWarm™ Cleave

Media for vitrification and warming of cleavage stage embryos.

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Rapid-i accessories

SmartBox 3™

Box for liquid nitrogen, used with
Rapid-i tools.

Rapid-i™ Sealer

Ultrasonic sealer for sealing Rapid-i Kits.

Rapid-i Cutter

For opening of Rapid-i straw.

Rapid-i™ Forceps

For retrieval of Rapid-i stick after opening.

Rapid-i™ CryoCane

Aluminum cryocane for storage of Rapid-i Kit in cryotank.

Rapid-i™ Goblet

Plastic goblet for holding straws used in cryopreservation.

SmartBox 3 to keep you well organised and safe 

The SmartBox 3 is designed to keep you safe and to improve your working comfort in the lab during vitrification. New product features provide a more seamless, predictable, and repeatable workflow.

Learn more about SmartBox 3

Proven success

Numerous publications show that Rapid-i Vitrification System provides excellent outcomes after vitrification of all stages, from oocytes to blastocysts. Independent published studies show that Rapid-i Vitrification System performs equally well as open vitrification systems and provides safe storage. 1,2  

 

Rapid-i Vitrification System – Summaries of selected studies

The Rapid-i Vitrification System has long been the natural choice for embryologists looking to optimise their vitrification workflow. In this document we have gathered the strongest clinical evidence between 2010-2022. It includes 14 published papers using products from the Rapid-i Vitrification System and demonstrates the efficiency and safety of the methodology.

Download summaries

Comparison of closed vs open vitrification devices

Vitrification is used for medically assisted reproduction and fertility preservation: the goal is to ensure the maximum survival rate with the highest level of biosafety. In this blog post, we will compare closed and open carrier devices for vitrification.

Read blog post

"The Rapid-i Vitrification System impacts our daily workflow in a positive way. It is fast, easy to use and repeatable amongst all embryologist"

- Glenn Proctor, MHA, Director of Laboratories, Conceptions Reproductive Associates of Colorado

Rapid-i Vitrification System - Tips & Tricks

This guide highlights practical tips and tricks for a successful vitrification. It contains 12 pages with text, images and illustrations explaining how to work the different steps in the process​.  

Download your copy now

Important factors for
successful vitrification

Download the white paper "How to be successful with vitrification" and learn more about factors influencing high survival rates in vitrification and warming.

Download white paper

Vitrolife Academy online training

This course cover the background and technical details surrounding the vitrification and warming of oocytes and embryos. You will learn more about the details surrounding the Vitrolife media and devices used during vitrification and warming as well as the associated protocols. This short video will give you an introduction to the online course. 

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Keep your embryos safe with the help of B:safe

A 24/7 monitoring trolley for liquid nitrogen storage tanks. Via its integrated balance, B:safe is able to dynamically follow and document the filling level of a storage tank and analyse liquid nitrogen consumption as a benchmark of the tank´s performance. Adding a second layer of safety, a temperature sensor continuously monitors the temperature of the tank´s outer shell and will promptly detect cooling in case of vacuum failure.

Read more about B:safe

Educational material

Do you need support in how to use our products? Or do you want to increase your knowledge?

Explore more

References

1. Desai NN, Goldberg JM, Austin C, Falcone T. The new Rapid-i carrier is an effective system for human embryo vitrification at both the blastocyst and cleavage stage. Reprod Biol Endocrinol. 2013 May 15;11:41.
2. Hashimoto S, Amo A, Hama S, Ohsumi K, Nakaoka Y, Morimoto Y. A closed system supports the developmental competence of human embryos after vitrification : Closed vitrification of human embryos. J Assist Reprod Genet. 2013 Mar;30(3):371-6.
3. Iwahata H, Hashimoto S, Inoue M, Inoue T, Ito K, Nakaoka Y, Suzuki N, Morimoto Y. Neonatal outcomes after the implantation of human embryos vitrified using a closed-system device. J Assist Reprod Genet. 2015 Apr;32(4):521-6.
4. Gook DA, Choo B, Bourne H, Lewis K, Edgar DH. Closed vitrification of human oocytes and blastocysts: outcomes from a series of clinical cases. J Assist Reprod Genet. 2016 Sep;33(9):1247-52.
5. Desai N, Ploskonka S, Goodman L, Attaran M, Goldberg JM, Austin C, Falcone T. Delayed blastulation, multinucleation, and expansion grade are independently associated with live-birth rates in frozen blastocyst transfer cycles. Fertil Steril. 2016 Nov;106(6):1370-1378.
6. Sciorio R, Thong KJ, Pickering SJ. Single blastocyst transfer (SET) and pregnancy outcome of day 5 and day 6 human blastocysts vitrified using a closed device. Cryobiology. 2018 Oct;84:40-45.
7. Sciorio R, Thong KJ, Pickering SJ. Increased pregnancy outcome after day 5 versus day 6 transfers of human vitrified-warmed blastocysts. Zygote. 2019 Oct;27(5):279-284.
8. Gunst J. et al, Data on file, 2019. Slow developing embryos undergoing compaction or cavitation on day 5 substantially contribute to live birth rates after single day 6 vitrified-warmed blastocyst transfer, P-135, 36th annual meeting of the Society for Human Reproduction and Embryology, 2020.
9. Balaban B, Isiklar A, Urman B, Gardner DK, Larman MG. Vitrification of human and mouse embryos using the Rapid-i. Fertil Steril. 2010 Sep;94(4): S115.
10. Pinasco M, Hickman T, Russell H, Rashiv B. Oocyte Vitrification Freeze/Thaw Survival Rates Using an Open Versus a Closed System. Fertil Steril. 2012 March;97(3):S18.
11. Machac S, Hubinka V, Larman M, Koudelka M. A novel method for human oocyte vitrification with a closed device using super-cooled air. Fertil Steril. 2013 Oct;100(3):S108.
12. Perez O, Tilley B, Navarrete G, Lay L, Little LM, Gada R, Chantilis S. Oocyte vitrification using a new vitrification medium and a new closed vitrification device. A sibling oocyte study. Fertil Steril. 2018 Sep;110(4):E179-E180.
13. Pujol A, Zamora MJ, Obradors A, Garcia D, Rodriguez A, Vassena R. Comparison of two different oocyte vitrification methods: a prospective, paired study on the same genetic background and stimulation protocol. Hum Reprod. 2019 Jun 4;34(6):989-997.

Support Documents

Documents Language

Rapid-i™ Vitrification System

Package inserts

English

Package insert Rapid-i Kit

Rapid-i™ Vitrification System

Short protocols

English

Short protocol - Rapid-i™ Vitrification Omni. For all stages, from oocytes to blastocysts

This short protocol describes how to vitrify and warm all cell stages from oocytes to blastocysts using Rapid-i ™vitrification system and RapidVit™/Warm™ Omni.

Rapid-i™ Vitrification System

Short protocols

English

Short protocol - Rapid- i™ Vitrification of oocytes

This short protocol describes how to vitrify and warm oocytes using Rapid-i™ vitrification system and RapidVit™/RapidWarm™ Oocyte.

Rapid-i™ Vitrification System

Short protocols

English

Short protocol - Rapid-i™ Vitrification of Cleavage stage embryos

This short protocol describes how to vitrify and warm cleavage stage embryos using Rapid-i™ vitrification system and RapidVit™/RapidWarm ™ Cleave.

Rapid-i™ Vitrification System

Short protocols

English

Short protocol - Rapid-i™ Vitrification System of blastocysts

This short protocol describes how to vitrify and warm blastocysts using Rapid-i™ vitrification system and RapidVit™/RapidWarm™ Blast.

Rapid-i™ Vitrification System

Scientific summaries

English

Rapid-i is an effective system for human embryo vitrification at both the blastocyst and cleavage stage

In this study, Desai et al, conclude that “Rapid-i offers an excellent alternative to existing open vitrification devices for both day 3 embryos and for blastocysts” at the same time as it prevents direct contacts between embryos and liquid nitrogen.

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