ICSI made safe, using recombinant human albumin.

Description Viscous sperm handling solution containing recombinant human albumin and PVP.

Purpose For the immobilisation and isolation of sperm prior to intracytoplasmic sperm injection, ICSI.

Application For use after pre-equilibration at +20 ± 5ºC and ambient atmosphere.

Storage Store dark at +2 to +8°C

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5 x 0.1 mL

Recombinant albumin for safety

ICSI is a viscous sperm handling solution designed to facilitate sperm immobilization and injection into the oocyte. It contains recombinant human albumin for safety and the most widely used molecule used for this purpose, polyvinylpyrrolidone or PVP. PVP is an inert molecule that does not take part in any metabolic pathway.

From scientific breakthrough to standard procedure

In 1992 science brought hope to thousands of childless couples when the first pregnancies generated by ICSI were reported. This meant that male infertility factor was less of an obstacle to starting a family.

At its introduction in the early 1990s, fertilisation rates after ICSI were around 30%.1 Thanks to further modifications of the procedure, fertilisation rates of over 80% are now possible and ICSI is now used as the method for fertilisation in around 65% of all treatment cycles globally.

REF 1. Joris, H. et al. Intracytoplasmic sperm injection: laboratory set-up and injection procedure. Hum Reprod. 1998 Apr;13 Suppl 1:76-86

Support Documents

Documents Language


Package inserts


Package insert ICSI

Document and Ref: REF 20430, version 09


Safety data sheets (SDS)



Document and Ref: Date Revised : 06/27/2023. Revision No : 6. Safety data sheet for ICSI


Short protocols


G-Series™ ICSI procedure

Document and Ref: REF 19122. Version 02. Date of issue 220923. This short protocol describes how to perform ICSI using ICSI™, HYASE™-10x, OVOIL™ and G-Series medium G-MOPS™ PLUS .


Short protocols


Gx-Series™ ICSI procedure

Document and Ref: REF 19179. Version 1. Date of issue 220923 This short protocol describes how to perform ICSI using ICSI™, HYASE™-10x, OVOIL™ and Gx-Series medium Gx-MOPS™ PLUS and Gx-TL™

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