G-TL™
The first culture medium specifically designed for time-lapse.
Description G-TL is a bicarbonate buffered medium containing hyaluronan and human serum albumin for culture of embryos from fertilisation to the blastocyst stage and for transfer. Gx-TL has a unique combination of triple antioxidant protection for improved embryo viability.
Purpose Medium for culture of embryos from fertilisation to the blastocyst stage.
Application For use after pre-equilibration at +37°C and 6 % CO2.
Storage Store dark at +2 to +8°C
For truly undisturbed time-lapse culture
Time-lapse culture removes time limits and stresses from embryos during assessment while adding power to classic morphology. G-TL is a medium in the G-Series™ designed to optimise the use of time-lapse technology, allowing truly undisturbed time-lapse culture.
Gx-TL has a unique triple antioxidant protection to improve embryo viablity. Acetyl-L-Carnitine, Alpha-Lipoic Acidand N-Acetyl-L-Cysteine are working together to protect the embryo from oxidative stress.
Gx-TL with triple antioxidant protection
Reactive oxygen species are ubiquitous throughout any given IVF cycle. And they pose a significant threat to your embryo culture. To keep your embryos out of harm’s way, we have developed a unique triple antioxidant protection for improved embryo viability. The three antioxidants have been added to our culture media, Gx-TL, to form a protective barrier against oxidative stress. Gx-TL is only for sale in US, Japan and India.
Learn more about GX Media
Balancing stresses
G-TL provides uninterrupted culture conditions in an optimised culture environment to maximise embryo viability. The balanced mix of amino acids in G-TL is based on new knowledge about embryo metabolism and consumption of media constituents1. G-TL is designed to reduce ammonium load from breakdown products, while providing an optimised supply of amino acids for development.
G-TL has been shown to give high results when compared to sequential culture systems as well as monophasic culture systems.
Why you should use specific
embryo culture media for
specific applications
Watch this movie where Dr. Silversand describes the development of G-TL as well as present clinical results from a multicentre prospective randomised trial.
Watch movie
Time-lapse technology triggers new requirements on embryo culture media
The introduction of time-lapse technology has reduced the need of handling the embryo outside the incubator. Time-lapse technology has given a unique possibility to balance metabolic stress against less handling stress during embryo culture. Learn more in this blog post.
Read blog postStudy confirms high
performance of G-TL
Watch Dr. Hardarson present results from an international, prospective, controlled and randomised multicentre study evaluating G-TL in a clinical environment using time-lapse technology.
This lecture was a part of the Vitrolife Scientific Symposium at ESHRE 2014.
Optimise all the way with G-Series
Ensure optimal conditions before, during and after culture by using the whole G-Series™. All G-Series media share the same basic composition to secure viability and implantation potential. Osmolality, pH and supporting compounds are all kept constant. This foundation prevents intracellular stresses as the embryos progress through the IVF process.
Support Documents
Documents Language
Package inserts
English
Package insert G-TL
Package insert G-TL. REF 26283 version 9.
Package inserts
English
Package insert GxTL
Package insert Gx-TL. REF 26902 version 4.
Safety data sheets (SDS)
English
SDS G-TL
Safety data sheet for G-TL
Safety data sheets (SDS)
English
SDS Gx-TL
Safety data sheet for Gx-TL
Product manuals
English
Manual G-Series. International
This manual describes how to use all media in the G-Series: G-RINSE, G-MOPS, G-GAMETE, G-IVF, G-1, G-2, G-TL, G-PGD, HSA-solution, G-MM, ICSI, HYASEx-10x, OVOIL , SpermGrad and EmbryoGlue.
Product manuals
English
Manual G-Series. For US
This manual describes how to use all media in the G-Series: G-RINSE, G-MOPS, G-GAMETE, G-IVF, G-1, G-2, G-TL, G-PGD, HSA-solution, G-MM, ICSI, HYASEx-10x, OVOIL, SpermGrad and EmbryoGlue
Short protocols
English
ICSI Procedure
Gx Series
Short protocols
English
Gx-TL Embryo Culture
1.181023.2
Short protocols
English
G-TL Embryo Culture
REF 19125 version 1. Date of issure 2019-08-12
Short protocols
English
Short protocol - Embryo culture Gx Series
This short protocol describes how to culture embryos from after fertilisation until the blastocyst stage using the G-Series™ sequential media G-1™ PLUS, G-2™ PLUS and OVOIL™.
Short protocols
English
Short protocol - Embryo Culture using G-TL™ with Primo Vision™ Time-lapse monitoring system
This short protocol describes handling of embryos for culture in Primo Vision time-lapse system using G-Series ™media G-MOPS™, G-MOPS™ PLUS, OVOIL™ and G-TL™.
Short protocols
English
Short protocol - Blastocyst trophectoderm biopsy
This short protocol describes how to perform blastocyst trophectoderm biopsy using OVOIL™ and G-Series™ media, G-2™ PLUS or G-TL™ and G-MOPS™ PLUS
Scientific summaries
English
G-TL supports blastocyst development in large volume
In a study presented at the ACE meeting in the UK, Shaw and co-workers compared single step time-lapse medium (Vitrolife, G-TL) with sequential series media (Sage, Quinn’s advantage) in large volume culture as well as micro drop culture. They found significantly higher day 5 blastocyst development rate in the G-TL group in both large and small volume culture.
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