Embryo decision support tools

Decision support tools scoring embryos according to their statistical viability by applying a number of criteria to the embryos.

Purpose Decision support tools to rank embryos according to their likelihood of implantation.

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iDAScore®

  • Description: Fully automated AI-based decision support tool for day 5 culture.
  • Purpose: AI Algorithm with automatic scoring of embryos, to improve workflow.

Disclaimer: Not for sale in US

  • Description: Optional AI-based tool to streamline annotation process.
  • Description: Embryo decision support tool software for Day 3 selection. KIDScore is a trademark of Vitrolife Group.
  • Description: Upgrade for existing KIDScore D3. KIDScore is a trademark of Vitrolife Group.

Disclaimer: Not for sale in US

  • Description: Embryo decision support tool software for Day 3 and Day 5 full package. KIDScore is a trademark of Vitrolife Group.

Disclaimer: Not for sale in US

  • Description: EmbryoViewer Thin Client with Monitor, keyboard and accessories version 7.X.
  • Description: EmbryoViewer Software version 7.X.
  • Description: ES Server Software version 7.X.

Advanced embryo evaluation interface

Data from multiple incubators is centralised on a server and accessed via EmbryoViewer workstations. Advanced embryo analysis software tools allow direct comparison of all of a patient’s embryos, both fresh and frozen, in a single interface.

EmbryoViewer Workstation

Intuitive interface to annotate, review movies and compare development of patient embryos. Full documentation of incubator running conditions are automatically stored with the patient data and can be observed on the EmbryoViewer workstation for quality assurance. It is easy to generate reports and create customised exports.

VTH Server

Our powerful server has been specially designed to support direct integration of our AI-based evaluation solutions. Centralised data provides a better opportunity for analysis of treatments and outcomes.
VTH server & VTH server+ replace current ES server and ES server+.

Embryo analysis software tools

iDAScore

iDAScore makes use of deep learning to provide fully automated analyses of developing embryos. Now you can get an objective ranking based on the likelihood of implantation of each of a patient´s embryos at once - at the touch of a button. The future of embryo evaluation begins here.

 

Artificial intelligence in the treatment of infertility

The advent of time-lapse technology in IVF has provided a platform that supports improved embryo culture and evaluation, as well as increasing knowledge about embryo development. Advances in artificial intelligence (AI) methods for image analysis allow us to take embryo evaluation to the next level.

The RCT study* published in Nature Medicine, demonstrates that iDAScore is 10x faster than standard manual assessment and provides similar clinical outcomes.

Learn the latest update
*Illingworth et. al 2024, Nature Medicine, in press.

Improved evaluation

Traditional embryo evaluation methods are prone to subjectivity and external factors. Experience level, time constraints and lab staffing may all affect evaluation of embryos. It has been shown that an embryologist may score the same blastocyst differently on separate occasions1,2. iDAScore® objectively “compares” a given embryo with other embryos that have similar development patterns, and generates a score correlating with the likelihood of implantation.

AI scoring is not affected by

 

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Fully automated analysis

iDAScore is an AI-based scoring system that provides fully automated analysis of time-lapse sequences. Now you can get an objective ranking based on the likelihood of achieving a fetal heartbeat on days 2, 3 or blastocyst stage of each of a patient’s embryos at once – with just a touch of a button.

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Improving the evaluation process

iDAScore provides a reliable ranking of all embryos, allowing you to use your time more efficiently in hands-on procedures.

 

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Consistent

Consistent approach to embryo evaluation. Day to day differences in staffing, or introduction of new embryologists will not affect the way embryos are scored.

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Objective

Objectively analyses the full embryo development sequence, without inherent human bias.

 

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Fully automated

Analyses time-lapse sequences continuously, without the need for manual processing of data or videos.

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Reliable

Provides a reliable ranking of a patient’s cohort of embryos. Embryos can be evaluated adjunctively with EmbryoViewer software or other well established scoring schemes.

 

Building on the power of AI

The iDAScore algorithm was developed by our own AI team and trained on full time-lapse sequences of now more than 180,000 time-lapse sequences of embryos with known clinical fate.

 

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Diverse data to minimise bias

Data diversity and size can reduce bias in AI-based embryo selection by providing the model with a more representative sample of the population it will be used on. Diversity in the dataset means that the model is exposed to a wide variety of input patterns, which allows it to learn from a broad range of examples such as patient profile and clinical protocols. This can help to prevent the model from becoming overly specialised to a specific subset of the population, wich can lead to bias.

The iDAScore input is comprised of a wide variety of data that have been collected across three continents.The data represents a wide variety of patient profile and clinical practices including oocyte origin, IVF and ICSI, clinical protocols, and patients’ age. It includes data from both fresh and frozen embryos with known outcome.

* KID Embryos: Embryos with Known Implantation Data

Performance of iDAScore

iDAScore has been validated to correlate with clinical outcomes including implantation and live birth.

Live birth rate increases by iDAScore group in all age groups3

Live Birth stratified by age of 3010 Single Vitrified Blastocyst transfers

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OR Live Birth 1.811 95% C.I. 1.666-1.976 p<0.05.
Multivariate adjusted OR 1.535 95%CI 1.358-1.736, p<0.05. P <0.05. for all age groups. OR = 1,811 (1.666-1.976).
aOR = 1.535 (1.358–1.736). n= # transfers in each age group.

Odds Ratio (OR), adjusted odds ratio (aOR).

The higher the iDAScore the higher the likelihood of implantation4

Implantation rate

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OR Oocyte donor    1.61     1.19-2.19     p<0.001
OR autologoous      1.52     1.22-1.90     p<0.001
Our findings confirm that embryo evaluation can be performed automatically allowing embryologists to utilise their time more efficiently in other tasks of the IVF process that are more complex and require high precision and attention.

Optimisation of workflows

The software is intuitive and simple to use, and images and videos don’t need to be converted manually.

 

Access from your EmbryoViewer workstation

iDAScore is an optional module which can be accessed from an updated interface on the EmbryoViewer workstation. Full documentation of incubator running conditions are automatically stored with the patient data and can be observed.

EmbryoViewer facilitates better opportunities for communication, consultation and education.

Scores for the entire cohort

A score (from 1 to 9.9) is automatically generated for each embryo in any individual patient’s cohort. iDAScore works for embryos starting from time of culture until blastocyst stage. A higher score indicates a greater chance of achieving a fetal heartbeat. Low priority embryos, including those with abnormal PN status, are automatically identified.

The improved iDAScore scoring for high scores allows better separation of high and low scores.

Ideal for prioritsation for further evaluation in your clinical practice

 

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iDAScore® - the future of AI-based embryo evaluation

Are you interested in learning more about how artificial intelligence can be used in IVF? Read this blog post by Dr. Tine Qvistgaard Kajhøj where she takes you through the evolution of Vitrolife’s AI-based tools for IVF. 

Read blog post

References

1. Bormann et. al (2020), Fertil Steril 113(4): 781-787.e1.
2. Storr et. al (2017), Hum Reprod 32(2): 307-314.
3. Ueno et al. (2022), JARG (39) 2089-2099.
4. Bori et al. (2022), Human Reproduction 37(Suppl.1).
5. Casciani et al. (2022), Human Reproduction 37(Suppl. 1).
6. Ezoe et al. (2022), Reprod Biomed Online 45(6):1124-1132.
7. Berntsen et al. (2022), PLoS ONE 17(2): e0262661.

Guided annotation

An optional tool in the EmbryoViewer software that is designed to provide a simplified annotation workflow.

Advanced software

With EmbryoViewer software, you can review, annotate and compare development of selected embryos from data acquired by the EmbryoScope+, EmbryoScope 8 and EmbryoScope Flex. The same EmbryoViewer software can be used for the three types of incubators. The incubators’ running conditions are automatically stored with the patient data and can be observed on the EmbryoViewer software for quality assurance.

Ensure consistent evaluation of embryos with Guided Annotation

With the extensive amount of image information acquired by the EmbryoScope time-lapse system, every stage of development of each embryo can be observed.Guided Annotation ensures that you collect exactly the amount and type of embryo development information that is necessary for you to evaluate which embryos are most suitable for transfer and/or freezing.

By implementing intelligent software tools and artificial intelligence, Guided Annotation makes embryo annotation fast, efficient and precise and allows you to have complete control of the level of automatisation. A confidence estimate allows you to automate annotations that have a high confidence level and prioritise validation of annotations with low confidence.

Intuitive annotation tools

With EmbryoViewer software, you can annotate cell division events, providing an easy overview of observations in developmental stages.

Improved basis for embryo selection

Use Guided Annotation in the EmbryoViewer software to efficiently get the parameters you need for embryo evaluation. Designed to provide a simplified annotation workflow.

KIDScore for efficient evaluation support

KIDScore™ decision support tools* assigns an objective score to each embryo. The scores reflect implantation potential and provide consistent and effective support for embryo evaluation. With Guided Annotation and KIDScore decision support tools you can customise to fit the workflow you like with the level of automatisation you prefer.

*KIDScore D5 has not received 510(k) clearance

KIDScore

KIDScore D3 & D5 makes a safe first model using avoidance critera rather than selection criteria - you can design and implement your own models.

Guided Annotation and KIDScore

Guided Annotation in synergy with KIDScore optimally supports your consistent embryo evaluation process.

Benefits of KIDScore

• Improves the decision-making process
• Enhances consistency
• Helps you obtain better results

  

KIDScore for transfer on Day 3 or Day 5

The KIDScore decision support tool is developed by analysing the world’s largest database of embryo development with known clinical outcome. The models are developed by analysing how embryo morphokinetics, cleavage patterns and morphology correlates with implantation outcome after transfer.

Principles of KIDScore D3

Benefits of KIDScore decision support tools

• Improved consistency of evaluation and lower interobserver variability5
• Uses ‘easy-to-annotate’ variables
• Based on Known Implantation Data (KID) from the day of transfer (Fetal heartbeat)
• A powerful tool when you have more embryos available than planned for transfer

KIDScore D3

When to use it
• When deciding between embryos that reach expected stage on day 3
• When D3 SET is preferred

How does it work?
KIDScore D3 assigns a morphokinetic score from 1-5 to your annotated embryos. The score from 1-5 is a relative measure of the implantation potential of the embryo. The following variables need to be annotated in accordance with specific guidelines: PN assessment, PN fading, time (t) to 2, 3, 4, 5 and 8 cells.

KIDScore D3 & implantation data
The chart represents unselected embryos, embryos chosen for transfer, implanted embryos and embryos resulting in a live birth from cycles where known outcome data is available. The distribution of embryos across score groups is shown. This indicates that there is excellent concordance between the model and embryos with high implantation potential.

KIDScore D5

When to use it? 

• When more good quality blastocysts are available than are planned for transfer
• When deciding which embryos are suitable for biopsy or diagnosis

How does it work?

KIDScore D5* considers the morphology and the morphokinetic traits of an embryo. For each embryo the model calculates a continuous score from 1-9.9. The score reflects the statistical chance of implantation based on development information from the five-day culture period. The higher the score, the greater the statistical chance of implantation. Only a few annotations are required to obtain a score, which further improves the worfklow.

KIDScore D5 & implantation data
KIDScore D5 scores show an increased relative implantation with higher scores. The model is based on a large database of KID blastocysts originating from a wide range of IVF clinics.

*KIDScore D5 can only be used when culturing under reduced oxygen conditions

How can you benefit from time-lapse in IVF?

Dr. Markus Montag has written a white paper where he discusses the clinically proven results with time-lapse, as well as how time-lapse can improve the workflow in the lab and facilitate communication. 

Download white paper

Watch our recorded Vitrolife webinars

Vitrolife Academy provides a wide range of webinars within the field of IVF. Our webinars are recorded and you can find them here, to watch at your convenience.

Explore webinars

Increase your knowledge with our educational material

Do you need support in how to use our products? Whether it's learning a new skill, gaining knowledge, or advancing your career, educational material is essential for achieving your goals.

Explore educational material

A complete solution with the world’s leading time-lapse systems

Vitrolife has everything your clinic needs to maximise time-lapse culture and evaluation. Whether you want to implement and enjoy the benefits of an integrated time-lapse system for 8, 15 or 24 patients or complement your current set-up with more time-lapse incubation capacity.

 

References

1. Ergin, E.G. et al., (2014), Fertil Steril 102(4): 1029-1033 e1.
2. Data on file.
3. Rubio, I. et al., (2012), Fertil Steril 98(6): 1458-63.
4. Zhan, Q. et al., (2016) PLoS One 11(12): e0166398. 
5. Sundvall, et al., (2013), Hum Reprod 28(12): 3215-21. 

Support Documents

Documents Language

Product manuals
Vitrolife security and privacy guide

Product manuals

English

Vitrolife security and privacy guide

Document and Ref: Revision 2023.12.22/International/English

Scientific summaries
iDAScore®

Scientific summaries

English

iDAScore Science publications and selected abstracts

Document and Ref: REF19196 v05 20241004

Product manuals
iDAScore®

Product manuals

English

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/English.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

English

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/English

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

English

EmbryoViewer User Manual

Document and Ref: Version 7.9, revised 2022.10.03/EU/English

Product manuals
KIDScore™

Product manuals

English

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/International/English

Product manuals
KIDScore™

Product manuals

English

KIDScore D3 Appendix

Document and Ref: Version 2.0, revised 2022.10.03/English

Product manuals
KIDScore™

Product manuals

English

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/International/English.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
Guided Annotation™

Product manuals

English

Guided Annotation Detailed Guidelines

Document and Ref: Version 7.9, first issue 2022.10.03/English

Product manuals
Guided Annotation™

Product manuals

English

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/English

Product manuals
ES Server

Product manuals

English

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/English

Product manuals
CohortView™

Product manuals

English

CohortView™ User Manual

Document and Ref: Version 1, revised 2021.01.25/English

Product manuals
EmbryoViewer®

Product manuals

English

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/English (US)

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KIDScore™

Product manuals

English

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/English (US)

Product manuals
KIDScore™

Product manuals

English

KIDScore D3 Appendix

Document and Ref: Version 2.0, revised 2022.10.03/English (US)

Product manuals
ES Server

Product manuals

English

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/English (US)

Product manuals
Vitrolife security and privacy guide

Product manuals

Chinese

Vitrolife security and privacy guide

Document and Ref: Revision 2023.12.22/Simplified Chinese.

Product manuals
iDAScore®

Product manuals

Chinese

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Traditional Chinese (Taiwan)

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Chinese

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Chinese (Simplified)

Disclaimer: iDAScore has not received 510(k) clearance
Product manuals
iDAScore®

Product manuals

Chinese

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Traditional Chinese (Taiwan)

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Chinese

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Chinese (Simplified)

Disclaimer: iDAScore has not received 510(k) clearance.
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KIDScore™

Product manuals

Chinese

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Traditional Chinese (Taiwan).

Product manuals
KIDScore™

Product manuals

Chinese

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Simplified Chinese.

Product manuals
KIDScore™

Product manuals

Chinese

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Traditional Chinese (Taiwan)

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Chinese

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Simplified Chinese

Disclaimer: KIDScore D5 has not received 510(k) clearance.
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KIDScore™

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KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Traditional Chinese (Taiwan)

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KIDScore™

Product manuals

Chinese

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Simplified Chinese.

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Guided Annotation™

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Chinese

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Chinese (traditional)

Product manuals
Guided Annotation™

Product manuals

Chinese

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Chinese (simplified)

Product manuals
ES Server

Product manuals

Chinese

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Traditional Chinese (Taiwan)

Product manuals
ES Server

Product manuals

Chinese

ES Server User Manual

Document and Ref: Version 7.9, revised 2022.11.04/Chinese (simplified)

Product manuals
EmbryoViewer®

Product manuals

Chinese

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/ Traditional Chinese (Taiwan)

Product manuals
EmbryoViewer®

Product manuals

Chinese

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Chinese (simplified)

Product manuals
iDAScore®

Product manuals

Czech

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Czech.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Czech

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Czech.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Czech

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Czech

Product manuals
KIDScore™

Product manuals

Czech

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Czech

Product manuals
KIDScore™

Product manuals

Czech

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Czech.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Czech

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Czech

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Guided Annotation™

Product manuals

Czech

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Czech

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ES Server

Product manuals

Czech

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Czech

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iDAScore®

Product manuals

Danish

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Danish.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Danish

iDAScore (1.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Danish.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Danish

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Danish

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KIDScore™

Product manuals

Danish

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Danish

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KIDScore™

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Danish

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Danish.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Danish

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Danish

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Guided Annotation™

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Danish

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Danish

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ES Server

Product manuals

Danish

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Danish

Product manuals
CohortView™

Product manuals

Danish

CohortView™ User Manual Danish

Document and Ref: Version 1, revised 2021.01.25/International/Danish

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iDAScore®

Product manuals

Estonian

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Estonian.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Estonian

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Estonian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
Embryo decision support tools

Product manuals

Estonian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Estonian

Product manuals
KIDScore™

Product manuals

Estonian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2021.08.02/Estonian

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KIDScore™

Product manuals

Estonian

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Estonian.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Estonian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Estonian

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Guided Annotation™

Product manuals

Estonian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Estonian

Product manuals
ES Server

Product manuals

Estonian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Estonian

Product manuals
iDAScore®

Product manuals

French

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/French

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

French

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/French

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

French

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/French

Product manuals
KIDScore™

Product manuals

French

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/French

Product manuals
KIDScore™

Product manuals

French

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/French.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

French

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/French

Product manuals
Guided Annotation™

Product manuals

French

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/French

Product manuals
ES Server

Product manuals

French

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/French

Product manuals
iDAScore®

Product manuals

German

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/German.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

German

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/German.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

German

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/German

Product manuals
KIDScore™

Product manuals

German

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/German

Product manuals
KIDScore™

Product manuals

German

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/German.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

German

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/German

Product manuals
Guided Annotation™

Product manuals

German

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/German

Product manuals
ES Server

Product manuals

German

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/German

Product manuals
CohortView™

Product manuals

German

CohortView™ User Manual German

Document and Ref: Version 1, revised 2021.01.25/International/German

Product manuals
iDAScore®

Product manuals

Greek

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Greek.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Greek

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Greek.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Greek

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Greek

Product manuals
KIDScore™

Product manuals

Greek

KIDScore D3 Appendix

Document and Ref: Version 2.0, revised 2022.10.03/Greek

Product manuals
KIDScore™

Product manuals

Greek

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/Greek

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Greek

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Greek

Product manuals
Guided Annotation™

Product manuals

Greek

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Greek

Product manuals
ES Server

Product manuals

Greek

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Greek

Product manuals
iDAScore®

Product manuals

Hungarian

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Hungarian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Hungarian

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Hungarian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Hungarian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Hungarian

Product manuals
KIDScore™

Product manuals

Hungarian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Hungarian

Product manuals
KIDScore™

Product manuals

Hungarian

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Hungarian.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Hungarian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Hungarian

Product manuals
Guided Annotation™

Product manuals

Hungarian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Hungarian

Product manuals
ES Server

Product manuals

Hungarian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Hungarian

Product manuals
iDAScore®

Product manuals

Italian

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Italian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Italian

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Italian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Italian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Italian

Product manuals
KIDScore™

Product manuals

Italian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Italian

Product manuals
KIDScore™

Product manuals

Italian

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Italian

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Italian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Italian

Product manuals
Guided Annotation™

Product manuals

Italian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Italian

Product manuals
ES Server

Product manuals

Italian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Italian

Product manuals
CohortView™

Product manuals

Italian

CohortView™ User Manual Italian

Document and Ref: Version 1, revised 2021.01.25/International/Italian

Product manuals
iDAScore®

Product manuals

Japanese

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Japanese

Disclaimer: iDAScore has not received 510(k) clearance
Product manuals
iDAScore®

Product manuals

Japanese

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Japanese

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Japanese

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Japanese

Product manuals
KIDScore™

Product manuals

Japanese

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Japanese

Product manuals
KIDScore™

Product manuals

Japanese

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Japanese

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Japanese

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Japanese

Product manuals
Guided Annotation™

Product manuals

Japanese

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Japanese

Product manuals
CohortView™

Product manuals

Japanese

CohortView™ User Manual Japanese

Document and Ref: Version 1, revised 2021.01.25/International/Japanese

Product manuals
iDAScore®

Product manuals

Latvian

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Latvian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Latvian

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Latvian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Latvian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Latvian

Product manuals
KIDScore™

Product manuals

Latvian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Latvian

Product manuals
KIDScore™

Product manuals

Latvian

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Latvian

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Latvian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Latvian

Product manuals
Guided Annotation™

Product manuals

Latvian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Latvian

Product manuals
ES Server

Product manuals

Latvian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Latvian

Product manuals
iDAScore®

Product manuals

Norwegian

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Norwegian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Norwegian

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Norwegian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Norwegian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Norwegian

Product manuals
KIDScore™

Product manuals

Norwegian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Norwegian

Product manuals
KIDScore™

Product manuals

Norwegian

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/Norwegian

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Norwegian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Norwegian

Product manuals
Guided Annotation™

Product manuals

Norwegian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Norwegian

Product manuals
ES Server

Product manuals

Norwegian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Norwegian

Product manuals
iDAScore®

Product manuals

Portuguese

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/International/Portuguese (Brazil)

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
Embryo decision support tools

Product manuals

Portuguese

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2024.02.10/Portuguese (Portugal)

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Portuguese

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Portuguese (Brazil)

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Portuguese

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Portuguese (Brazil)

Product manuals
EmbryoViewer®

Product manuals

Portuguese

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Portuguese

Product manuals
KIDScore™

Product manuals

Portuguese

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Portuguese (Brazil)

Product manuals
KIDScore™

Product manuals

Portuguese

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Portuguese (Portugal).

Product manuals
KIDScore™

Product manuals

Portuguese

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/Portuguese (Brazil)

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Portuguese

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Portuguese (Portugal)

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Portuguese

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Portuguese (Brazil)

Product manuals
KIDScore™

Product manuals

Portuguese

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Portuguese (Portugal).

Product manuals
Guided Annotation™

Product manuals

Portuguese

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.11.04/Portuguese (Brazil)

Product manuals
Guided Annotation™

Product manuals

Portuguese

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Portuguese (Portugal)

Product manuals
ES Server

Product manuals

Portuguese

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Portuguese (Brazil)

Product manuals
ES Server

Product manuals

Portuguese

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Portuguese (Portugal)

Product manuals
iDAScore®

Product manuals

Russian

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Russian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Russian

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Russian

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Russian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Russian

Product manuals
KIDScore™

Product manuals

Russian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Russian

Product manuals
KIDScore™

Product manuals

Russian

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/Russian

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Russian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Russian

Product manuals
Guided Annotation™

Product manuals

Russian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Russian

Product manuals
ES Server

Product manuals

Russian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Russian

Product manuals
EmbryoViewer®

Product manuals

Serbian

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Serbian

Product manuals
KIDScore™

Product manuals

Serbian

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Serbian.

Product manuals
KIDScore™

Product manuals

Serbian

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Serbian.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Serbian

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Serbian.

Product manuals
Guided Annotation™

Product manuals

Serbian

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Serbian

Product manuals
ES Server

Product manuals

Serbian

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Serbian

Product manuals
iDAScore®

Product manuals

Spanish

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Spanish.

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Spanish

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Spanish

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Spanish

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Spanish

Product manuals
KIDScore™

Product manuals

Spanish

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Spanish.

Product manuals
Embryo decision support tools

Product manuals

Spanish

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Spanish.

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Spanish

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Spanish

Product manuals
Guided Annotation™

Product manuals

Spanish

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Spanish

Product manuals
ES Server

Product manuals

Spanish

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Spanish

Product manuals
iDAScore®

Product manuals

Swedish

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Swedish

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
iDAScore®

Product manuals

Swedish

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Swedish

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Swedish

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Swedish

Product manuals
KIDScore™

Product manuals

Swedish

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Swedish

Product manuals
KIDScore™

Product manuals

Swedish

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/Swedish

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Swedish

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Swedish

Product manuals
Guided Annotation™

Product manuals

Swedish

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Swedish

Product manuals
ES Server

Product manuals

Swedish

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Swedish

Product manuals
iDAScore®

Product manuals

Turkish

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Turkish

Disclaimer: iDAScore has not received 510(k) clearance
Product manuals
iDAScore®

Product manuals

Turkish

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Turkish

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Turkish

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Turkish

Product manuals
KIDScore™

Product manuals

Turkish

KIDScore D3 Appendix

Document and Ref: Version 2.0, revised 2022.10.03/Turkish

Product manuals
KIDScore™

Product manuals

Turkish

KIDScore D5 Appendix

Document and Ref: Version 3.0, revised 2022.10.03/Turkish.

Disclaimer: KIDScore D5 has not received 510(k) clearance
Product manuals
KIDScore™

Product manuals

Turkish

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4, revised 2022.10.03/Turkish

Product manuals
Guided Annotation™

Product manuals

Turkish

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Turkish

Product manuals
ES Server

Product manuals

Turkish

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Turkish

Product manuals
iDAScore®

Product manuals

Vietnamese

iDAScore (1.0) User Manual

Document and Ref: Version 1, revised 2021.03.22/Vietnamese

Disclaimer: iDAScore has not received 510(k) clearance
Product manuals
iDAScore®

Product manuals

Vietnamese

iDAScore (2.0) User Manual

Document and Ref: Version 2, revised 2022.12.12/Vietnamese

Disclaimer: iDAScore has not received 510(k) clearance.
Product manuals
EmbryoViewer®

Product manuals

Vietnamese

EmbryoViewer User Manual

Document and Ref: Version 7.9, first issue 2022.10.03/Vietnamese

Product manuals
KIDScore™

Product manuals

Vietnamese

KIDScore D3 Appendix

Document and Ref: Version 2, revised 2022.10.03/Vietnamese.

Product manuals
KIDScore™

Product manuals

Vietnamese

KIDScore D5 Appendix

Document and Ref: Version 3, revised 2022.10.03/Vietnamese

Disclaimer: KIDScore D5 has not received 510(k) clearance.
Product manuals
KIDScore™

Product manuals

Vietnamese

KIDScore Decision Support Tool User Manual

Document and Ref: Version 4.0, revised 2022.10.03/Vietnamese

Product manuals
Guided Annotation™

Product manuals

Vietnamese

Guided Annotation Quick Guide

Document and Ref: Version 7.9, first issue 2022.10.03/Vietnamese

Product manuals
ES Server

Product manuals

Vietnamese

ES Server User Manual

Document and Ref: Version 7.9, first issue 2022.11.04/Vietnamese

Technotes
KIDScore™

Technotes

English

Technote KIDScore D3 decision support tool

Document and Ref: Technote This technote describes the KIDScore D3 Basic, which is a model based on the morphokinetic traits associated with the implantation potential of embryos transferred on day 3. The model is designed to help clincs avoid transferring embryos with low implantation potential.

Technotes
Embryo decision support tools

Technotes

English

Technote Guidelines for blastocyst morphology grading with time-lapse

Document and Ref: This technote describes the grading of blastocyst morphology with the use of time-lapse technology. This facalitates a more thorough evaluation because the complete course of development can be considered. A comprehensive impression of the blastocyst can be used as the basis for grading morphology, which should be utilised when grading ICM and TE and is neccessary when using KIDScore D5.

Technotes
Embryo decision support tools

Technotes

English

Technote - Consistent annotation for better evaluation - a guide on definitions for morphokitetics

Document and Ref: This technote describes the definitions of variables most commonly used in embryo assessment with time-lapse. These definitions will help you attain consistent annotations and thereby objective evaluations in your clinic and further streamline the understanding of embryo developmental events within the clinic and beyond the clinic.

Technotes
KIDScore™

Technotes

English

KIDScore D5 decision support tool

Document and Ref: KIDScore D5 decision support tool, Vitrolife, v3 INT, December 2021. This technote describes the KIDScore D5, which is a model based on morphology and morphokinetic traits associated with the implantation potential of embryos transferred on day 5. The model is designed to help clincs avoid transferring embryos with low implantation potential.

Technotes
Embryo decision support tools

Technotes

English

Guidelines for getting started with models in Compare & Select

Document and Ref: Technote Guidelines for getting started with models in Compare & Select, Vitrolife, v6 INT, March 2015. This technote gives you simple starting tips to make the most of your data when using morphokinetics to build a model customised for your clinic.

Technotes
Guided Annotation™

Technotes

English

Guided Annotation - setting up the tool

Document and Ref: Guided Annotation 2.0: setting up, Vitrolife, v5, July 2021. This technote describes how the Guided Annotation tool is set up in a completely customidable way to support the needs and strategies of your clinical workflow. This tool is designed to support the busy workdays in the laboratory and guides you from variable to the next in an annotation strategy and by automatically forwarding the embryo images to estimated timings of events. Guided Annotation in synergy with KIDScore models optimally supports your consistent embryo assessment process.

Technotes
Guided Annotation™

Technotes

English

Guided Annotation - daily workflow

Document and Ref: Guided Annotation v2.0: daily workflow, Vitrolife, v5, July 2021. This technote is about the Guided Annotation tool, which is designed to support the busy workdays in the laboratory. The tool guides you from variable to the next in an annotation strategy and by automatically forwarding the embryo images to estimated timings of events. Guided Annotation in synergy with KIDScore models optimally supports your consistent embryo assessment process.

Technotes
EmbryoViewer®

Technotes

English

Tracking individual outcome in EmbryoViewer software

Document and Ref: Technote Tracking individual outcome in EmbryoViewer software, Vitrolife, v2, November 2019. This technote gives an overview of how to track individual transfer outcome in the EmbryoViewer software.

Technotes
Embryo decision support tools

Technotes

English

Effect and prevalence of embryo developmental traits

Document and Ref: Effect and prevalence of embryo developmental traits, Vitrolife, v1 INT, June 2016. This technote contains a summary of the prevalence and effect of developmental traits which can only be observed with time-lapse.

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